Do you ask for 'literature review asparaginase'? Here you can find questions and answers on this topic.
Elspar is a microorganism enzyme that is used as AN antineoplastic agent, for the most part in the therapy of acute white blood corpuscle leukemia. L-asparaginase has many side personal effects, one of which is hepatic accidental injury that is characterised by inhibition of hepatic protein deductive reasoning and steatosis, which can be stern and lead to death from viscus failure.Latency: 26 daysMedication: Asparaginase (dose non given)Pattern: Cholestatic (Severity: 5+ (jaundice, viscus failure and death)
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Our cases and review of the literature show that l-asparaginase is a viable treatment alternative in relapsed nk/t- extranodal lymphoma.
Objectives: this article is an overview of commonly encountered asparaginase-associated toxicities and offers recommendations for treatment management.
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Underlying obesity and/or diabetes may represent risk factors.
L-asparagine
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Historically treated with asparaginase-free regimens.
A literature brushup of peg-induced htg in adults incontestible similar results: symptomless presentation despite identical severe htg.
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Treatment was temporarily interrupted because of toxicity in 14 patients, and for good discontinued in AN additional 31.
Gui wolfram, yang b, shen q, bai k wang j, guan t, zhao J wang j and su l: in treatment with l-asparaginase-based regimen for basal pulmonary nk/t cadre lymphoma: a case report and brushup of the lit.
L-asparaginase side effects
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The hunting was conducted connected five databases: lilacs, pubmed, science absolute, scopus and entanglement of science upbound until july 20th, 2016, with nary time or language.
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Derangement of clotting can be from l-asparaginase, used to treat acute lymphoblastic leukemia.
Extranodal nasal-type biological killer/t-cell lymphoma with penile involvement: A case report and review of the literature.
Whether the pegylated form is of particular benefit testament require further cogitation.
Sci-hub
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This drug depletes the enzyme, therefore decrescendo the amound of fibrinogen, plasminogen, antithrombin iii, protein hundred, and protein s.
View article: google scholar: pubmed/ncbi.
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We critically reviewed the European country language literature pertaining to drug-induced pancreatitis and attempted to determine whether the reported association betwixt each drug and pancreatitis was valid.
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Oxaliplatin induces a delayed-action immune-mediated hemolytic anemia: a case account and review of the literature.
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Findings: the rapid designation and management of common asparaginase-associated unfavourable events can contract symptom severity and limit potential interruptions.
Chyloperitoneum, or chylous ascites, is a infrequent condition characterized away milky-appearing fluid with elevated triglyceride self-satisfied and the mien of chylomicrons.
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Aggressive nk-cell leukemia is a rare malignance with neoplastic proliferation of natural cause of death cells.
Spectrila l-asparaginase
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Fashionable 13 patients, this occurred before 10 doses of l-asparaginase were given, piece in the left 18 patients, therapy was stopped aft remission was attained.
The purpose of this systematic review was to identify the available literature of the l-asparaginase producing fungi.
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Asparaginase is a part of combination chemotherapy for acute lymphoblastic leukemia.
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As AN alternative, we rich person been studying Elspar ii from Saccharomyces cerevisiae, coded aside asp3 gene, which was cloned and expressed in pichia pastoris.
L-asparaginase structure
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Fungal gathering of l-asparaginase exploitation solid-state fermentation: A review sally naser1,2;wesameldin saber3;mohammad el-metwally4,*;mahmoud moustafa5,6;attalla el-kott5,7 1 aliveness sciences department, college of science and literature mahyel aseer, king khalid university, abha, saudi Arabia 2 unit of food bacteriology, bifocal laboratory of intellectual nourishment hygiene, ministry of health, branch stylish zagazig.
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L-asparaginase mechanism of action
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The disease is usually unsusceptible to cytotoxic agents, and no discourse has emerged every bit the standard of care for these patients.
Less convincing, simply suggestive evidence exists for: 1-asparaginase.
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Peg-asparaginase based multidrug chemotherapy is actual for refractory disseminated extranodal nk/t-cell lymphoma with leptomentigeal involvement: a clinical case report and brushup of literature hong chenga, d, tatyana feldmanb, kar F
Last Update: Oct 2021
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Comments
Venona
22.10.2021 03:00
Likewise according to lit reports the exercis of l-asparaginase from plants for discourse of acute lymphoblastic leukemia has been studied less 17.
It often presents with constitutional symptoms, A rapid declining medical institution course, and A poor prognosis with a median endurance of a a couple of months.
Letarsha
26.10.2021 05:48
The following drugs appear to cause pancreatitis: azathioprine, thiazides, sulfonamides, furosemide, estrogens, and tetracycline.
Htg is letter a rare but clinically important adverse outcome of peg.
Estefania
25.10.2021 07:58
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The search was conducted on 5 databases: lilacs, pubmed, science direct, scopus and web of science up unt.
Furlon
20.10.2021 02:14
Methods: a literature brushup was conducted, reviewing asparaginase and standard toxicities, speci cally hypersensitivity, pancreatitis, thrombo .
Objectives: this clause is an overview of commonly encountered asparaginase- associated toxicities and o ers recommendations for discourse management.