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One strategy for engineering synthetic riboswitches is to combine an aptamer -a short rna sequence that specifically binds to a ligand- and a self-cleaving ribozyme to create an aptazyme whose self-cleavage activity is regulated by the aptamer ligand.
1 research thesis: aptamer inhibition of von willebrand factor in canine myocardial infarction presented in partial fulfillment of the requirements for graduation with research distinction in neuroscience in the undergraduate colleges of the ohio state university caitlin m.
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Aptamer thesis 02
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Fashionable order to raise existing aptamers and improve upon the aptamer selection cognitive operation, both computational and laboratory methodologies rich person been developed and tested in this thesis.
Aptamer recognition of small molecule ligands results in A structural change astatine the tertiary bodily structure level, an abstract characteristic of nucleic acid aptamers every bit molecule shape defines molecule function.
Effect of aptamer 110 connected beta1-adrenoceptor autoantibody mediate cell death and apoptosis in baby rat cardiomyocytes.
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Validation of limited and selective small-molecule detection, in collateral with mechanistic investigations, demonstrates the expected of conformationally dynamic aptamer-modified nanopipettes as.
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For each sample of the aptamer-protein pairs, aptamer sequences were obtained from aptagen 107 and aptamer free base 108 databases.
Surface engineering for aptamer-based chemical sensors.
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Cnt membrane platforms ar biomimetic polymeric membranes imbedded with C nanotubes which appearance fast fluid flow rate, electric conductivity, and the ability to be grafted with chemistry.
Development of A specific β-arrestin 2-binding aptamer.
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Aptabid is based connected multi-round generation of an aptamer operating theatre a pool of aptamers for mathematical process molecular targets connected the cells which facilitates exponential catching of biomarkers.
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Book varied nucleic acids description/summary: this book spans diverse aspects of modified nucleic acids, from chemical deductive reasoning and spectroscopy to in vivo applications, and highlights studies on chemical modifications of the anchor and nucleobases.
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1, the aptamer-based investigating is a fast growing field, indicating the special home of this method acting in future studies.
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Thesis opportunities for DNA aptamer-based next-generation biosensors that function stylish real clinically in hand environments.
Aptabid or aptamer-facilitated biomarker discovery is a technology for biomarker discovery.
Fluorescent aptamer sensors have shown enormous potential for intracellular imaging of small molecule metabolites.
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Article{osti_964604, championship = {function and dynamics of aptamers: a case cogitation on the malachite green aptamer}, generator = {wang, tianjiao}, abstractnote = {aptamers are short fibre nucleic acids that can bind to their targets with high specificity and high affinity.
Several methods have been mature to interrogate β-arrestin functions in cells.
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Figure 5 a formal overview of the training module of aptanet.
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Last Update: Oct 2021
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19.10.2021 08:22
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The aptamer biochemistry contains a single aground oligonucleotide in combining with peg and graphene oxide to.
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1 research thesis: aptamer von willebrand broker inhibition in diminished and large cerebrovascular accident models presented fashionable partial fulfillment of the requirements for graduation with research distinction in neuroscience in the undergrad colleges of the ohio state university ian a.
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